分析名词+介词+which的语法结构,如the extent to which

分析名词+介词+which的语法结构,如the extent to which
Write a response in which you discuss the extent to which you agree or disagree with the statement and explain your reasoning for the position you take. In developing and supporting your position, be sure to address the most compelling reasons and/ or examples that could be used to challenge your position.句子中的名词+介词+which结构分析.
这里可不可以把 response in which 里的in which 换成where，如果不能什么情况下可以？